On September 1, the European Commission officially banned TPO (diphenylphosphine oxide) and DMTA (dimethyl-p-toluidine), substances used in semi-permanent nail polishes, considering them reproductive toxins and endocrine disruptors (Regulation (EU) 2025/877).
TPO is a photoinitiator that poses higher risk during application, as it can be inhaled or come into contact with the skin of nail technicians. DMTA, on the other hand, is an adhesive activator considered even more dangerous, as it hardens and polymerizes without the need for light or heat, remaining active for longer periods.
Experts warn that the most affected individuals are beauty professionals, given their continuous exposure during working hours.
What is Colombia’s position?
Colombia is part of the Andean Community (CAN), which issues regional decisions on cosmetic product regulations. Colombia has already filed a priority request before the CAN Secretariat to review the potential risks of products containing TPO and DMTA. However, so far the CAN has not issued a ruling banning these substances.
As for adverse events, the Invima (Colombia’s National Food and Drug Surveillance Institute) has stated that no adverse reactions have been identified to date in relation to nail polishes containing these substances. Nevertheless, on September 9, 2025, Invima issued a statement urging the public to report any suspected adverse effects.
In Colombia, cosmetics are mainly regulated under Andean Decision 833 of 2018 and complementary national provisions issued by Invima. To date, neither the CAN nor Colombia has expressly prohibited the use of TPO or DMTA. However, INVIMA has encouraged manufacturers and importers to review their formulations, adopt preventive measures, and report any adverse events. This highlights a regulatory gap compared to the European standard and may anticipate future restrictions in the Colombian market.
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At Nieto Lawyers, we advise cosmetic sector companies in complying with national and international regulations, mitigating legal and reputational risks.
Does your company manufacture or import cosmetic products? Contact us and we will guide you through the steps to take in light of this emerging regulation.
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Frequently Asked Questions (FAQs)
Has Colombia already banned TPO and DMTA in nail polishes?
No. As of today, neither the Andean Community nor Invima has issued an explicit ban. However, the EU has already included these substances on its restricted list, which may anticipate regulatory changes in Colombia.
What regulations apply to cosmetics in Colombia?
Mainly Andean Decision 833 of 2018 and Invima’s national resolutions, which establish requirements for safety, labeling, and mandatory sanitary notification.
What should manufacturers and importers do today?
Review formulations, reinforce biosafety measures, report any adverse events, and evaluate safer alternatives. It is also highly recommended to seek legal advice to mitigate regulatory risks.
